Description

5-Iodo-2-Nitrobenzoic Acid is a halogenated nitrobenzoic acid derivative that serves as a versatile and valuable synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both an iodine substituent and a nitro group ortho to the carboxylic acid, makes it a critical building block for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring halogenated aromatic scaffolds.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and other crop protection agents.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Building block for organic electronic materials, liquid crystals, and polymers where nitro and iodo functionalities are required.
• Dye and Pigment Intermediate: Utilized in the synthesis of complex organic dyes and colorants.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form biaryl structures.

Basic Information

Product Name	5-Iodo-2-Nitrobenzoic Acid
CAS No.	35674-28-3
Molecular Formula	C7H4INO4
Molecular Weight	293.02 g/mol
Synonyms	2-Nitro-5-iodobenzoic Acid; 5-Iodo-2-nitrobenzoic Acid; Benzoic acid, 5-iodo-2-nitro-; 5-Iodo-2-nitro-benzoic acid; 2-Nitro-5-iodo-benzoic acid; 5-Iodo-o-nitrobenzoic acid; NSC 403820
EINECS	Contact for details

Quality Control

Our 5-Iodo-2-Nitrobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in a dark place.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.