Description

3,4-Diiodobenzoic Acid is a high-purity iodinated aromatic carboxylic acid, serving as a versatile and critical building block in advanced organic synthesis. Its value lies in the strategic placement of iodine atoms, which act as excellent leaving groups for cross-coupling reactions or as sites for further functionalization. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for thyroid hormone analogs and other iodine-containing drug molecules.
• Agrochemical Synthesis: Used as a building block for creating novel herbicides, fungicides, and plant growth regulators that require halogenated aromatic structures.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings due to the reactivity of the iodine substituents.
• Chemical Biology & Labeling: Utilized in the synthesis of probes and tags for biochemical research and diagnostic applications.
• Organic Synthesis Reagent: A versatile reagent for introducing the diiodobenzoic acid moiety into more complex molecular architectures.

Basic Information

Item	Details
Product Name	3,4-Diiodobenzoic Acid
CAS No.	35674-20-5
Molecular Formula	C7H4I2O2
Molecular Weight	373.92 g/mol
Synonyms	3,4-Diiodobenzoic Acid; Benzoic acid, 3,4-diiodo-; 3,4-DIIODOBENZOIC ACID; 3,4-Diiodobenzoicacid; 3,4-Diiodo-benzoic acid; NSC 404083; 3,4-Diiodobenzoic Acid (CAS 35674-20-5); 3,4-Diiodobenzoic acid, 98%
EINECS	Contact for details

Quality Control

Our 3,4-Diiodobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	255 - 260 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.