Description

n-Methyl-n-Nitroso-2-Butanamine is a specialized nitrosamine compound with the CAS number 35606-37-2. This chemical is a critical intermediate and research chemical, valued for its role in synthetic organic chemistry and analytical method development. It is primarily sought by research institutions and industrial laboratories engaged in pharmaceutical development, toxicology studies, and advanced material synthesis.

Application

• Pharmaceutical Research & Development: Used as a key intermediate in the synthesis of complex organic molecules and active pharmaceutical ingredients (APIs).
• Analytical Chemistry Standard: Serves as a reference standard and calibrant in chromatographic analysis (GC, HPLC) for nitrosamine detection and quantification.
• Toxicology and Safety Studies: Employed as a model compound in mutagenicity and carcinogenicity research to understand biological pathways and establish safety thresholds.
• Chemical Synthesis: Acts as a versatile building block for introducing the N-nitroso functional group into target molecules in organic synthesis.
• Material Science Research: Investigated for potential applications in the development of specialty polymers and advanced functional materials.
• Regulatory Compliance Testing: Utilized by quality control laboratories to validate analytical methods for nitrosamine impurities in compliance with ICH M7(R1) and other regulatory guidelines.

Basic Information

Product Name	n-Methyl-n-Nitroso-2-Butanamine
CAS No.	35606-37-2
Molecular Formula	C5H12N2O
Molecular Weight	116.16 g/mol
Synonyms	N-Nitroso-N-methyl-2-butanamine; N-Methyl-N-nitroso-2-butanamine; 2-Butanamine, N-methyl-N-nitroso-; N-Nitroso-N-methylbutylamine; N-Methyl-N-nitrosobutylamine; MNBA; N-Nitroso-N-methylbutan-2-amine
EINECS	Contact for details

Quality Control

Our n-Methyl-n-Nitroso-2-Butanamine is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity assay by chromatography (HPLC/GC), and determination of related substances. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or quality specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at controlled room temperature (15-25°C). Due to its highly volatile and easily oxidized nature, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.