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4-Bromo-6,8-Dichloroquinoline CAS NO 35478-81-0
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CAS No.:35478-81-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
4-Bromo-6,8-Dichloroquinoline is a halogenated quinoline derivative serving as a versatile and high-value synthetic building block in advanced organic chemistry. Its core value lies in its functionalized aromatic structure, which enables precise molecular construction for creating complex, biologically active compounds. This intermediate is critically needed by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.
Application
- Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting infectious diseases or cancer.
- Agrochemical Research: Used in developing new generations of herbicides, fungicides, and pesticides with enhanced efficacy.
- Material Science: Serves as a building block for creating organic semiconductors, ligands for metal-organic frameworks (MOFs), or specialty dyes.
- Chemical Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the quinoline scaffold into more complex molecules.
- Academic & R&D: Essential for medicinal chemistry programs and methodological studies in universities and contract research organizations (CROs).
Basic Information
| Product Name | 4-Bromo-6,8-Dichloroquinoline |
| CAS No. | 35478-81-0 |
| Molecular Formula | C9H4BrCl2N |
| Molecular Weight | 276.95 g/mol |
| Synonyms | 6,8-Dichloro-4-bromoquinoline; Quinoline, 4-bromo-6,8-dichloro-; 4-Bromo-6,8-dichlor-chinolin; 35478-81-0; 4-Br-6,8-Cl-Quinoline |
| EINECS | Contact for details |
Quality Control
Our 4-Bromo-6,8-Dichloroquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to minimize exposure to moisture and atmospheric contaminants.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Melting Point | Contact for details |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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