Description

Dl-α-Bromo-β-(5-Imidazolyl)Propionic Acid CAS NO 35319-96-1 is a specialized brominated heterocyclic carboxylic acid derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both an imidazole ring and a reactive α-bromo acid moiety, makes it a valuable building block for constructing complex molecules with targeted biological activity. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in medicinal chemistry and the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of histamine H3 receptor antagonists and other pharmacologically active imidazole-containing compounds.
• Medicinal Chemistry Research: Employed as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new drug candidates.
• Bioconjugation & Probe Synthesis: Used to create chemical probes and affinity labels for studying biological systems due to its reactive bromo group.
• Peptidomimetic Development: Incorporated into peptide analogs to modulate stability, bioavailability, and receptor interaction.
• Agrochemical Research: Serves as an intermediate in the development of novel fungicides and herbicides that leverage the imidazole pharmacophore.
• Academic & Industrial R&D: Utilized in organic synthesis laboratories for methodological development and the creation of novel heterocyclic libraries.

Basic Information

Product Name	Dl-α-Bromo-β-(5-Imidazolyl)Propionic Acid
CAS No.	35319-96-1
Molecular Formula	C6H7BrN2O2
Molecular Weight	219.04 g/mol
Synonyms	DL-α-Bromo-β-(5-imidazolyl)propionic Acid; (±)-2-Bromo-3-(1H-imidazol-5-yl)propanoic Acid; 3-(1H-Imidazol-5-yl)-2-bromopropanoic Acid; 2-Bromo-3-(1H-imidazol-4-yl)propionic Acid (tautomer); Bromoimidazolylpropionic Acid; NSC 113928; DL-2-Bromo-3-(5-imidazolyl)propionic Acid; α-Bromo-β-(imidazol-5-yl)propionic Acid
EINECS	Contact for details

Quality Control

Our Dl-α-Bromo-β-(5-Imidazolyl)Propionic Acid is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP starting material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry conditions to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.