Description

(4-Amino-Phenyl)-Propiolic Acid CAS NO 35283-05-7 is a specialized aromatic amino acid derivative featuring both an amino group and a propiolic acid moiety. This unique bifunctional structure makes it a valuable high-purity building block for advanced organic synthesis and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a conjugated acetylene linker.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators.
• Material Science: Monomer or cross-linking agent for advanced polymers, dendrimers, and conductive organic materials.
• Bioconjugation & Probe Development: Used in creating fluorescent probes, bioconjugates, and molecular imaging agents via click chemistry reactions.
• Organic Synthesis: Versatile reagent for Sonogashira coupling and other palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Ligand Synthesis: Starting material for preparing chelating ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	(4-Amino-Phenyl)-Propiolic Acid
CAS No.	35283-05-7
Molecular Formula	C9H7NO2
Molecular Weight	161.16 g/mol
Synonyms	4-Aminophenylpropiolic Acid; p-Aminophenylpropiolic Acid; 4-Ethynylaniline-2-carboxylic Acid; 4-Aminobenzene propiolic acid; 2-Propynoic acid, 3-(4-aminophenyl)-; 3-(4-Aminophenyl)prop-2-ynoic acid
EINECS	Contact for details

Quality Control

Our (4-Amino-Phenyl)-Propiolic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring reproducible and reliable performance in critical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	205 - 210 °C (dec.)
Loss on Drying	≤ 2.0 %
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.