Description

(Ar)-2,2'-Dimethoxy-1,1'-Binaphthalene-3,3'-Dicarboxylic Acid is a high-purity, axially chiral binaphthyl derivative, a crucial building block in asymmetric synthesis and advanced materials science. Its value lies in its rigid, pre-organized structure which serves as a privileged scaffold for constructing chiral ligands, catalysts, and functional polymers. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require enantiomerically pure intermediates for developing novel active ingredients and high-performance materials.

Application

• Chiral Ligand & Catalyst Synthesis: A key precursor for developing BINOL and BINAP-type ligands used in asymmetric hydrogenation, C-C bond formation, and other enantioselective catalytic reactions.
• Pharmaceutical Intermediates: Serves as a sophisticated chiral building block for the synthesis of complex drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Advanced Material Precursors: Used in the creation of chiral organic frameworks (COFs), liquid crystals, and polymers with specific optical or electronic properties.
• Agrochemical Development: Employed in the research and production of enantiomerically pure pesticides and herbicides for enhanced efficacy and environmental safety.
• Analytical Chiral Stationary Phases: Can be functionalized for use in High-Performance Liquid Chromatography (HPLC) columns to separate enantiomers.
• Academic & Industrial R&D: A fundamental reagent for methodological development in organic chemistry and catalysis research.

Basic Information

Product Name	(Ar)-2,2'-Dimethoxy-1,1'-Binaphthalene-3,3'-Dicarboxylic Acid
CAS No.	35216-66-1
Molecular Formula	C24H18O6
Molecular Weight	402.40 g/mol
Synonyms	(aR)-2,2'-Dimethoxy-1,1'-binaphthalene-3,3'-dicarboxylic acid; (R)-2,2'-Dimethoxy-1,1'-binaphthyl-3,3'-dicarboxylic Acid; (R)-3,3'-Dicarboxy-2,2'-dimethoxy-1,1'-binaphthyl; (R)-DMBD; (R)-2,2'-Dimethoxy-1,1'-binaphthalene-3,3'-dicarboxylic acid; (R)-(-)-2,2'-Dimethoxy-1,1'-binaphthalene-3,3'-dicarboxylic acid; (R)-BINOL-3,3'-dicarboxylic acid dimethyl ether derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and manufacturing. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and optical rotation measurement to confirm identity, chiral purity (enantiomeric excess), and chemical purity. Certificates of Analysis (COA) detailing all relevant specifications are available upon request. We adhere to a quality management system to ensure batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Specific Optical Rotation	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.