Description

(-)-Cincholoiponic Acid CAS NO 35167-97-6 is a high-purity, optically active organic acid of significant interest in advanced chemical synthesis. This compound serves as a critical chiral building block and intermediate for the development of pharmaceuticals and fine chemicals. It is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise stereochemistry is paramount for product efficacy and safety.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and metabolic disorders.
• Asymmetric Synthesis: Employed as a chiral auxiliary or resolving agent to induce stereoselectivity in complex organic reactions.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Agrochemical Research: Serves as a building block for developing novel, enantiomerically pure herbicides and pesticides.
• Catalyst Ligand Synthesis: Utilized in the preparation of chiral ligands for asymmetric catalysis.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research laboratories.

Basic Information

Product Name	(-)-Cincholoiponic Acid
CAS No.	35167-97-6
Molecular Formula	C10H16O4
Molecular Weight	200.23 g/mol
Synonyms	(-)-Cincholoiponic Acid; (3R,4S)-3,4-Dihydroxy-4-isopropyl-1,2,3,4-tetrahydroquinoline-3-carboxylic Acid; Cincholoiponic Acid; L-Cincholoiponic Acid; (3R,4S)-1,2,3,4-Tetrahydro-3,4-dihydroxy-4-(1-methylethyl)-3-quinolinecarboxylic Acid; 3-Carboxy-3,4-dihydroxy-4-isopropyl-1,2,3,4-tetrahydroquinoline; A degradation product of Cinchona alkaloids.
EINECS	Contact for details

Quality Control

Our (-)-Cincholoiponic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.