Description

Boc-Gly-Nh2 CAS NO 35150-09-5 is a protected amino acid derivative, specifically N-Boc-glycinamide, widely used as a crucial building block in peptide synthesis. Its primary value lies in providing a stable, orthogonal protecting group for the amino terminus, enabling the controlled construction of complex peptide sequences. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors developing novel therapeutic peptides and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental reagent for the sequential assembly of peptides on resin.
• Solution-Phase Peptide Synthesis: Used in classical coupling strategies for producing custom peptides and peptide fragments.
• Pharmaceutical Intermediate: Serves as a key starting material in the research and development of peptide-based active pharmaceutical ingredients (APIs).
• Bioconjugation: Employed to introduce glycinamide linkers or spacers into biomolecules for drug delivery systems and diagnostic tools.
• Chemical Biology Research: Utilized in the synthesis of peptide mimetics, enzyme substrates, and inhibitors for biochemical studies.
• Combinatorial Chemistry: A valuable building block for generating diverse peptide libraries for screening and discovery.

Basic Information

Product Name	Boc-Gly-Nh2
CAS No.	35150-09-5
Molecular Formula	C7H14N2O3
Molecular Weight	174.20 g/mol
Synonyms	N-(tert-Butoxycarbonyl)glycinamide; Glycinamide, N-[(1,1-dimethylethoxy)carbonyl]-; Boc-Glycinamide; (tert-Butoxycarbonylamino)acetamide; 2-[(tert-Butoxycarbonyl)amino]acetamide; BOC-Gly-NH2; N-Boc-glycinamide; Nα-Boc-glycinamide
EINECS	Contact for details

Quality Control

Our Boc-Gly-Nh2 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive applications like peptide synthesis. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep the container tightly sealed after each use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	142 - 148 °C
Specific Rotation	Contact for details
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.