Description

(4Ar)-4A,5,6,7,8,8Aβ-Hexahydro-3-(1-Hydroxy-1-Methylethyl)-4A,5β-Dimethylnaphthalen-2(1H)-One is a high-purity, complex decalin-based ketone compound valued for its unique stereochemistry and functional groups. This specialty intermediate is critical for advanced organic synthesis, particularly in the development of novel pharmaceutical actives and fine chemicals. It serves as a key chiral building block for research and production chemists in the pharmaceutical, agrochemical, and fragrance industries seeking to introduce specific structural motifs into target molecules.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex therapeutic agents, including steroids and terpenoid-derived pharmaceuticals.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its decalin core structure.
• Fragrance & Flavor Chemistry: Serves as a starting material for the synthesis of sophisticated musk and woody aroma chemicals.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex polycyclic frameworks and natural product analogs.
• Catalyst & Ligand Development: Potential precursor for novel chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for creating specialized polymers with unique properties.

Basic Information

Product Name	(4Ar)-4A,5,6,7,8,8Aβ-Hexahydro-3-(1-Hydroxy-1-Methylethyl)-4A,5β-Dimethylnaphthalen-2(1H)-One
CAS No.	35124-22-2
Molecular Formula	C₁₇H₂₈O₂
Molecular Weight	264.40 g/mol
Synonyms	4a,5,6,7,8,8a-Hexahydro-3-(1-hydroxy-1-methylethyl)-4a,5-dimethylnaphthalen-2(1H)-one; (4aR,5S,8aS)-5,8a-Dimethyl-3-(2-hydroxypropan-2-yl)-4,4a,5,6,7,8-hexahydronaphthalen-2(1H)-one; 2(1H)-Naphthalenone, 4a,5,6,7,8,8a-hexahydro-3-(1-hydroxy-1-methylethyl)-4a,5-dimethyl-, (4aR,5S,8aS)-; Ambrosin derivative; Decalin ketone derivative; Sesquiterpene lactone intermediate
EINECS	Contact for details

Quality Control

Our production of (4Ar)-4A,5,6,7,8,8Aβ-Hexahydro-3-(1-Hydroxy-1-Methylethyl)-4A,5β-Dimethylnaphthalen-2(1H)-One adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and MS, to ensure it meets precise customer specifications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.