Description

5-Bromo-2-Hydroxy-3-Methoxybenzoic Acid is a versatile halogenated benzoic acid derivative that serves as a key synthetic intermediate in advanced organic chemistry. Its unique substitution pattern makes it a valuable building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, especially those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators due to its bioactive scaffold.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed coupling reactions and asymmetric synthesis.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and advanced polymers where its bromo and hydroxy groups allow for further functionalization.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological processes and protein interactions.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis, including cross-coupling and functional group transformation reactions.

Basic Information

Product Name	5-Bromo-2-Hydroxy-3-Methoxybenzoic Acid
CAS No.	35090-76-7
Molecular Formula	C8H7BrO4
Molecular Weight	247.04 g/mol
Synonyms	3-Methoxy-5-bromosalicylic Acid; 5-Bromo-3-methoxysalicylic Acid; 5-Bromo-2-hydroxy-3-methoxybenzoic acid; 2-Hydroxy-3-methoxy-5-bromobenzoic Acid; Benzoic acid, 5-bromo-2-hydroxy-3-methoxy-; 5-Bromovanillic Acid (common name); 35090-76-7
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Hydroxy-3-Methoxybenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (HPLC), identification (IR, NMR), and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.