Description

(1S-Trans)-1,2-Cyclohexanediamine Dihydrochloride is a high-purity, chiral diamine salt widely utilized as a critical building block and chiral ligand in advanced organic synthesis. Its primary value lies in enabling the production of enantiomerically pure compounds, which is essential for developing pharmaceuticals and specialty chemicals with high biological activity. This compound is particularly sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for applications in asymmetric catalysis and the synthesis of complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infectives.
• Asymmetric Catalyst Ligand: Serves as a crucial component in chiral catalysts for enantioselective hydrogenation and other asymmetric transformations.
• Agrochemical Synthesis: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and chiral compound libraries.
• Coordination Chemistry: Acts as a chelating agent for metal complexes used in materials science and catalysis.

Basic Information

Product Name	(1S-Trans)-1,2-Cyclohexanediamine Dihydrochloride
CAS No.	35018-62-3
Molecular Formula	C6H14N2·2HCl
Molecular Weight	195.11 g/mol
Synonyms	(1S,2S)-1,2-Diaminocyclohexane Dihydrochloride; (1S,2S)-Cyclohexane-1,2-diamine Dihydrochloride; (1S,2S)-1,2-DACH·2HCl; (1S,2S)-DACH Dihydrochloride; (1S,2S)-trans-1,2-Diaminocyclohexane Dihydrochloride; (S,S)-1,2-Diaminocyclohexane Dihydrochloride; (S,S)-DACH·2HCl; trans-(1S,2S)-1,2-Cyclohexanediamine Dihydrochloride
EINECS	Contact for details

Quality Control

Our (1S-Trans)-1,2-Cyclohexanediamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with stringent specifications for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.