Description

(S)-2-Bromo-3-Phenylpropionic Acid is a chiral, non-natural amino acid derivative characterized by a bromine atom at the α-carbon position. This compound serves as a versatile and high-value chiral building block in asymmetric synthesis, enabling the construction of complex molecules with precise stereochemical control. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors, enzyme inhibitors, and other bioactive molecules requiring the (S)-configuration.
• Agrochemical Synthesis: Used in the research and production of chiral herbicides and pesticides where stereochemistry impacts biological activity.
• Peptidomimetics & Drug Discovery: Incorporated into peptide analogs to enhance metabolic stability, bioavailability, and target selectivity.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in enantioselective transformations.
• Material Science Research: Employed in the synthesis of chiral polymers and functional organic materials with specific optical properties.
• Academic & R&D Laboratories: A standard reagent for methodological studies in organic chemistry and asymmetric synthesis.

Basic Information

Product Name	(S)-2-Bromo-3-Phenylpropionic Acid
CAS No.	35016-63-8
Molecular Formula	C9H9BrO2
Molecular Weight	229.07 g/mol
Synonyms	(S)-2-Bromo-3-phenylpropanoic acid; (S)-α-Bromohydrocinnamic acid; (S)-3-Phenyl-2-bromopropionic acid; (2S)-2-Bromo-3-phenylpropanoic acid; (S)-Bromo phenyl propionic acid; L-2-Bromo-3-phenylpropionic acid; (S)-2-Br-3-Ph-propionic acid
EINECS	Contact for details

Quality Control

Our (S)-2-Bromo-3-Phenylpropionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis (HPLC, Chiral GC), to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.