Description

2,2-Dimethyl-6-Azaspiro[2.5]Octa-4,7-Diene-6-Carboxylic Acid Ethyl Ester is a specialized spirocyclic organic compound that serves as a valuable synthetic intermediate in advanced organic chemistry. Its unique fused-ring structure makes it a critical building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. This high-purity intermediate is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those requiring complex spirocyclic or bridged-ring scaffolds.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical space and biological activity.
• Process Chemistry Development: Serves as a critical starting material or intermediate in the scale-up and optimization of API manufacturing routes.
• Agrochemical Synthesis: Potential building block for developing new crop protection agents with unique modes of action.
• Material Science Research: Investigated as a monomer or precursor for creating novel polymers with specific thermal or mechanical properties.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and catalysis.

Basic Information

Item	Details
Product Name	2,2-Dimethyl-6-Azaspiro[2.5]Octa-4,7-Diene-6-Carboxylic Acid Ethyl Ester
CAS No.	34995-40-9
Molecular Formula	C12H17NO2
Molecular Weight	207.27 g/mol
Synonyms	Ethyl 2,2-dimethyl-6-azaspiro[2.5]octa-4,7-diene-6-carboxylate; 6-Azaspiro[2.5]octa-4,7-diene-6-carboxylic acid, 2,2-dimethyl-, ethyl ester; 2,2-Dimethyl-6-azaspiro[2.5]octa-4,7-diene-6-carboxylic acid ethyl ester; Ethyl 2,2-dimethyl-6-azaspiro[2.5]octa-4,7-diene-6-carboxylate; 34995-40-9; Spirocyclic azetidine ester; Azaspiro[2.5]octadiene derivative.
EINECS	Contact for details

Quality Control

Our production of 2,2-Dimethyl-6-Azaspiro[2.5]Octa-4,7-Diene-6-Carboxylic Acid Ethyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the exacting standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment, and we support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere (e.g., nitrogen or argon) to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.