Description

(4R)-6-Methyl-4,8-Dihydroxy-3,4-Dihydronaphthalene-1(2H)-One is a chiral, dihydroxylated tetralone derivative with a defined stereocenter, serving as a critical synthetic intermediate and building block in advanced organic chemistry. Its value lies in its structural complexity, which enables the synthesis of more elaborate molecules, particularly in the pharmaceutical and fine chemical sectors. This compound is essential for R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), natural product analogs, and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug molecules, particularly those with tetralin or naphthalene-based scaffolds.
• Fine Chemical Synthesis: Used as a versatile building block for constructing natural products, fragrances, and advanced organic materials.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development and study of new stereoselective synthetic methodologies.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Academic & Industrial R&D: Fundamental research tool for exploring new chemical reactions and synthesizing novel compound libraries.

Basic Information

Product Name	(4R)-6-Methyl-4,8-Dihydroxy-3,4-Dihydronaphthalene-1(2H)-One
CAS No.	34987-22-9
Molecular Formula	C11H12O3
Molecular Weight	192.21 g/mol
Synonyms	(4R)-6-Methyl-4,8-dihydroxy-3,4-dihydro-1(2H)-naphthalenone; (R)-6-Methyl-4,8-dihydroxy-1-tetralone; 4,8-Dihydroxy-6-methyl-1-tetralone (R-enantiomer); (4R)-4,8-Dihydroxy-6-methyl-3,4-dihydro-1(2H)-naphthalenone; (R)-4,8-Dihydroxy-6-methyl-1,2,3,4-tetrahydronaphthalen-1-one; 34987-22-9; (R)-enantiomer of 6-Methyl-4,8-dihydroxy-1-tetralone
EINECS	Contact for details

Quality Control

Our (4R)-6-Methyl-4,8-Dihydroxy-3,4-Dihydronaphthalene-1(2H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profiles is available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.