Description

Rac-(1R,2R)-2-(3-Bromophenyl)Cyclopropane-1-Carboxylic Acid is a high-purity chiral cyclopropane derivative, a crucial advanced pharmaceutical intermediate (API) and versatile synthetic building block. Its value lies in the unique structural and stereochemical properties of the cyclopropane ring, which is strategically incorporated into active molecules to modulate their biological activity, metabolic stability, and physicochemical profile. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries, particularly for the synthesis of novel therapeutic agents and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders, antiviral agents, and other therapeutic areas.
• Agrochemical Synthesis: Used as a building block for developing novel pesticides and herbicides, where the cyclopropane moiety can enhance biological efficacy and environmental stability.
• Ligand & Catalyst Development: Serves as a chiral scaffold for creating novel ligands and organocatalysts used in asymmetric synthesis to produce enantiomerically pure compounds.
• Material Science Research: Employed in the development of advanced organic materials, such as liquid crystals or polymers with specific optical or electronic properties.
• Chemical Biology Probes: Utilized in medicinal chemistry to create molecular probes for studying enzyme mechanisms and protein-ligand interactions.
• Custom Synthesis & Process R&D: A critical starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis and route scouting for complex molecules.

Basic Information

Product Name	Rac-(1R,2R)-2-(3-Bromophenyl)Cyclopropane-1-Carboxylic Acid
CAS No.	34919-34-1
Molecular Formula	C10H9BrO2
Molecular Weight	241.08 g/mol
Synonyms	(±)-trans-2-(3-Bromophenyl)cyclopropanecarboxylic Acid; rac-(1R,2R)-2-(3-Bromophenyl)cyclopropanecarboxylic Acid; 2-(3-Bromophenyl)cyclopropanecarboxylic Acid (racemic trans isomer); trans-2-(m-Bromophenyl)cyclopropanecarboxylic Acid; 3-Bromophenylcyclopropanecarboxylic Acid; BCPCA; Cyclopropane-1-carboxylic acid, 2-(3-bromophenyl)-, (1R,2R)-rel-
EINECS	Contact for details

Quality Control

Our Rac-(1R,2R)-2-(3-Bromophenyl)Cyclopropane-1-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high chemical purity, correct stereochemistry, and consistent performance. Standard quality checks include chiral purity analysis (HPLC), identity confirmation (IR, NMR), and quantification of residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99:1 dr (trans:cis)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.