Description

6-Chloro-1,2,3,4-Tetrahydroquinoline-8-Carboxylic Acid is a versatile and synthetically valuable heterocyclic building block. This compound is essential for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and advanced organic materials. It is primarily sought after by the pharmaceutical, agrochemical, and specialty chemical industries for its role as a key intermediate in complex synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its fused quinoline structure.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport or emissive layer materials in advanced display technologies.
• Ligand and Catalyst Development: Employed in the preparation of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: Acts as a monomer or functional unit in the development of polymers and advanced organic materials with specific optical or electronic properties.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical testing, method development, and quality control in regulatory and R&D laboratories.

Basic Information

Product Name	6-Chloro-1,2,3,4-Tetrahydroquinoline-8-Carboxylic Acid
CAS No.	34849-21-3
Molecular Formula	C10H10ClNO2
Molecular Weight	211.65 g/mol
Synonyms	8-Carboxy-6-chloro-1,2,3,4-tetrahydroquinoline; 6-Chloro-1,2,3,4-tetrahydro-8-quinolinecarboxylic Acid; 6-Chloro-8-carboxy-1,2,3,4-tetrahydroquinoline; 6-Chlorotetrahydroquinoline-8-carboxylic Acid; 6-Chloro-1,2,3,4-tetrahydroquinoline-8-carboxylate; 34849-21-3; 6-Chloro-THQ-8-COOH
EINECS	Contact for details

Quality Control

Our 6-Chloro-1,2,3,4-Tetrahydroquinoline-8-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.