Description

1,2,3,4-Tetrahydro-Quinoline-8-Carboxylic Acid is a versatile heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. Its core value lies in its fused quinoline-tetrahydroquinoline structure, which serves as a key precursor for synthesizing complex pharmacologically active molecules. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors, dyes, and fluorescent markers due to its conjugated system.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and for custom synthesis projects in CROs (Contract Research Organizations).

Basic Information

Product Name	1,2,3,4-Tetrahydro-Quinoline-8-Carboxylic Acid
CAS No.	34849-19-9
Molecular Formula	C10H11NO2
Molecular Weight	177.20 g/mol
Synonyms	8-Quinolinecarboxylic acid, 1,2,3,4-tetrahydro-; 1,2,3,4-Tetrahydro-8-quinolinecarboxylic acid; Tetrahydroquinoline-8-carboxylic acid; 1,2,3,4-Tetrahydroquinoline-8-carboxylic acid; 8-Carboxy-1,2,3,4-tetrahydroquinoline; 1,2,3,4-Tetrahydro-8-quinolincarboxylic acid; THQ-8-COOH
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydro-Quinoline-8-Carboxylic Acid is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.