Description

(R)-1-Amino-3-Chloro-2-Propanol Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate. This compound matters for its role in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and fine chemicals, where stereochemical integrity is critical. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing chiral drugs and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the production of β-blockers, antimicrobial agents, and other enantiopure active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and manufacturing of chiral herbicides, fungicides, and plant growth regulators.
• Asymmetric Catalyst Ligand Precursor: Serves as a starting material for the synthesis of chiral ligands used in asymmetric catalysis.
• Fine Chemical Production: Employed in the synthesis of complex, high-value specialty chemicals requiring specific stereochemistry.
• Bioconjugation & Linker Chemistry: Utilized in the development of antibody-drug conjugates (ADCs) and other bioconjugates due to its reactive amino and chloro groups.
• Academic & Industrial Research: A valuable reagent for methodological development in organic synthesis and medicinal chemistry research.

Basic Information

Product Name	(R)-1-Amino-3-Chloro-2-Propanol Hydrochloride
CAS No.	34839-14-0
Molecular Formula	C3H9Cl2NO
Molecular Weight	158.01 g/mol
Synonyms	(R)-3-Chloro-2-hydroxypropylamine hydrochloride; (R)-1-Chloro-3-amino-2-propanol hydrochloride; (R)-3-Amino-1-chloro-2-propanol hydrochloride; (R)-1-Amino-3-chloro-2-propanol HCl; (R)-3-Chloro-1-amino-2-propanol hydrochloride; (R)-Chlorohydrin amine hydrochloride; (R)-Glycidylamine hydrochloride derivative; (R)-Aminochloropropanol HCl
EINECS	Contact for details

Quality Control

Our (R)-1-Amino-3-Chloro-2-Propanol Hydrochloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.