Description

4-(n-Maleimido)Benzyl-α-Trimethylammonium Iodide is a specialized heterobifunctional crosslinking reagent featuring a maleimide group and a quaternary ammonium moiety. This compound is critical for creating stable covalent bonds between thiol-containing molecules and surfaces or other biomolecules under mild aqueous conditions. It is primarily utilized by researchers and manufacturers in the life sciences sector for advanced bioconjugation, protein labeling, and the development of diagnostic assays and therapeutic agents.

Application

• Bioconjugation and Protein Labeling: Used to covalently attach peptides, proteins, or antibodies to surfaces, nanoparticles, or other biomolecules via thiol-maleimide chemistry.
• Diagnostic Assay Development: Serves as a key linker in the fabrication of biosensors, lateral flow assays, and ELISA kits for enhanced detection sensitivity.
• Therapeutic Agent Synthesis: Employed in the research and development of antibody-drug conjugates (ADCs) and other targeted drug delivery systems.
• Immobilization Chemistry: Facilitates the stable attachment of biomolecules to solid supports such as beads, chips, and membranes for chromatography and microarray applications.
• Polymer and Material Science: Acts as a functional monomer or crosslinker for synthesizing advanced polymeric materials with specific biological activity or surface charge properties.

Basic Information

Product Name	4-(n-Maleimido)Benzyl-α-Trimethylammonium Iodide
CAS No.	34696-66-7
Molecular Formula	C15H19IN2O2
Molecular Weight	386.23 g/mol
Synonyms	4-(N-Maleimidomethyl)benzyltrimethylammonium Iodide; N-(4-Trimethylammoniobenzyl)maleimide Iodide; 4-(Maleimidomethyl)benzyltrimethylammonium Iodide; 4-Maleimidobenzyltrimethylammonium Iodide; TMA-Maleimide; Q-Maleimide; (4-(Trimethylammonio)benzyl)maleimide Iodide; MBTAI
EINECS	Contact for details

Quality Control

Our 4-(n-Maleimido)Benzyl-α-Trimethylammonium Iodide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and bioconjugation applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccation and under an inert atmosphere to maintain optimal stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.