Description

4-Chloro-2-Chloromethylquinazoline is a versatile and highly functionalized quinazoline derivative that serves as a critical synthetic intermediate. Its molecular structure, featuring two reactive chlorine atoms at distinct positions, makes it a valuable building block for constructing complex heterocyclic systems. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of quinazoline-based drug candidates, including kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science Research: Used in the creation of advanced organic materials, such as ligands for metal-organic frameworks (MOFs) or organic semiconductors.
• Chemical Biology Probes: Serves as a scaffold for designing molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specialized heterocyclic chemistry.

Basic Information

Product Name	4-Chloro-2-Chloromethylquinazoline
CAS No.	34637-41-7
Molecular Formula	C9H6Cl2N2
Molecular Weight	213.06 g/mol
Synonyms	2-(Chloromethyl)-4-chloroquinazoline; 4-Chloro-2-(chloromethyl)quinazoline; Quinazoline, 4-chloro-2-(chloromethyl)-; 2-Chloromethyl-4-chloroquinazoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Chloromethylquinazoline is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.