Description

2-(Hydroxymethyl)Quinazolin-4(3H)-One is a versatile quinazolinone derivative, a key heterocyclic building block prized for its reactive hydroxymethyl group. This compound is essential for researchers and manufacturers developing novel active pharmaceutical ingredients and advanced organic materials. It is primarily utilized in pharmaceutical R&D for the synthesis of potential drug candidates and in fine chemical production for creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel quinazoline-based drug candidates, particularly for oncology and CNS research.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex heterocyclic scaffolds via reactions at the hydroxymethyl group.
• Agrochemical Research: Serves as a starting material for developing new active ingredients for crop protection products.
• Material Science: Investigated for the development of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probe: Utilized in academic and industrial research to study enzyme interactions and biological pathways.
• Custom Synthesis: A foundational compound for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	2-(Hydroxymethyl)Quinazolin-4(3H)-One
CAS No.	34637-40-6
Molecular Formula	C9H8N2O2
Molecular Weight	176.17 g/mol
Synonyms	2-(Hydroxymethyl)-4(3H)-quinazolinone; 4(3H)-Quinazolinone, 2-(hydroxymethyl)-; 2-Hydroxymethyl-4-quinazolinone; 2-Hydroxymethylquinazolin-4(3H)-one; Quinazolin-4(3H)-one, 2-(hydroxymethyl)-; 2-Methanol-4(3H)-quinazolinone
EINECS	Contact for details

Quality Control

Our 2-(Hydroxymethyl)Quinazolin-4(3H)-One is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.