Description

2-[[1-(α,α,α-Trifluoro-m-Tolyl)-1H-Pyrazolo[3,4-B]Pyridin-3-Yl]Oxy]Ethanol is a high-value, fluorinated heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its molecular architecture, featuring a pyrazolopyridine core linked to a trifluoromethylated aromatic system via an ethoxy linker, makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought after by research institutions and industrial R&D departments focused on medicinal chemistry, crop protection, and materials science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and central nervous system (CNS) disorders.
• Agrochemical Research: Serves as a core scaffold for developing next-generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Chemical Biology Probe: Used in academic and industrial research to create molecular probes for studying enzyme function and biological pathways.
• Material Science: Potential intermediate for synthesizing specialty polymers and advanced organic electronic materials due to its fluorinated aromatic system.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	2-[[1-(α,α,α-Trifluoro-m-Tolyl)-1H-Pyrazolo[3,4-B]Pyridin-3-Yl]Oxy]Ethanol
CAS No.	34580-74-0
Molecular Formula	C₁₆H₁₂F₃N₃O₂
Molecular Weight	335.28 g/mol
Synonyms	2-{[1-(3-Trifluoromethylphenyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]oxy}ethanol; 1-(3-Trifluoromethylphenyl)-1H-pyrazolo[3,4-b]pyridin-3-ol, 2-hydroxyethyl ether; 2-[[1-(3-Trifluoromethylphenyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]oxy]ethanol; 2-((1-(3-(Trifluoromethyl)phenyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)oxy)ethanol; Ethanol, 2-[[1-[3-(trifluoromethyl)phenyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]oxy]-
EINECS	Contact for details

Quality Control

Our production of 2-[[1-(α,α,α-Trifluoro-m-Tolyl)-1H-Pyrazolo[3,4-B]Pyridin-3-Yl]Oxy]Ethanol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.