Description

N8-Acetylspermidine Dihydrochloride is a chemically modified derivative of the naturally occurring polyamine spermidine, stabilized as a dihydrochloride salt for research and development applications. This compound is of significant interest in biochemical and pharmacological research due to its role in cellular metabolism and potential as a biomarker or modulator of polyamine pathways. It is primarily utilized by researchers and manufacturers in the life sciences sector, including pharmaceutical R&D, diagnostic development, and academic institutions focused on cell biology and metabolic studies. CAS NO 34450-15-2.

Application

• Biochemical Research: Used as a standard or reagent in studies investigating polyamine metabolism, acetylation processes, and their effects on cellular function.
• Pharmaceutical Development: Serves as a key intermediate or reference compound in the discovery and development of therapeutics targeting polyamine-related pathways, such as in oncology or neurology.
• Diagnostic Assay Development: Employed in the calibration and development of analytical methods (e.g., LC-MS/MS, ELISA) for the quantification of acetylated polyamines in biological samples.
• Enzymology Studies: Acts as a substrate for enzymes like spermidine/spermine N1-acetyltransferase (SSAT) to study enzyme kinetics and inhibition.
• Nutritional and Cosmetic Research: Investigated for its potential role in anti-aging, autophagy, and cellular health within nutraceutical and cosmeceutical research pipelines.

Basic Information

Product Name	N8-Acetylspermidine Dihydrochloride
CAS No.	34450-15-2
Molecular Formula	C9H23Cl2N3O
Molecular Weight	260.21 g/mol
Synonyms	N8-Acetylspermidine 2HCl; N8-Acetylspermidine Dihydrochloride; N8-Acetylspermidine Hydrochloride; 1,8-Diamino-4-aza-8-acetamidooctane Dihydrochloride; Spermidine, N8-acetyl-, dihydrochloride; N8-Acetylspermidine HCl; Acetylspermidine Dihydrochloride; N8-Ac-Spd
EINECS	Contact for details

Quality Control

Our N8-Acetylspermidine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets high-purity standards suitable for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.