Description

(2As,4R,5Aα,6S,8Aβ)-3α-Acetyl-4,7α-Dimethyl-6-Phenyldecahydro-1H-Pyrrolo[2,1,5-De]Quinolizine-4,6-Diol is a complex, high-purity alkaloid derivative with a defined stereochemistry. This compound matters as a sophisticated chiral building block and reference standard for advanced pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors for the synthesis and analysis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of complex drug candidates, particularly those targeting neurological and metabolic pathways.
• Reference Standard: Used as a high-purity analytical standard for method development, validation, and quality control in pharmaceutical analysis (HPLC, LC-MS).
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore and optimize biological activity of new chemical entities.
• Asymmetric Synthesis: Utilized as a starting material or catalyst ligand in stereoselective synthesis due to its multiple chiral centers.
• Biochemical Research: Acts as a tool compound for probing enzyme interactions and receptor binding studies in vitro.
• Process Chemistry Development: Supports route scouting and scale-up optimization for the production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	(2As,4R,5Aα,6S,8Aβ)-3α-Acetyl-4,7α-Dimethyl-6-Phenyldecahydro-1H-Pyrrolo[2,1,5-De]Quinolizine-4,6-Diol
CAS No.	34443-74-8
Molecular Formula	C22H31NO4
Molecular Weight	373.49 g/mol
Synonyms	3α-Acetyl-4,7α-dimethyl-6-phenyldecahydro-1H-pyrrolo[2,1,5-de]quinolizine-4,6-diol; 4,6-Dihydroxy-4,7α-dimethyl-6-phenyl-3α-acetyldecahydro-1H-pyrrolo[2,1,5-de]quinolizine; (2aS,4R,5aα,6S,8aβ)-3α-Acetyl-4,7α-dimethyl-6-phenyldecahydro-1H-pyrrolo[2,1,5-de]quinolizine-4,6-diol; Alkaloid C-22 Derivative; Pyrroloquinolizinediol derivative
EINECS	Contact for details

Quality Control

Our (2As,4R,5Aα,6S,8Aβ)-3α-Acetyl-4,7α-Dimethyl-6-Phenyldecahydro-1H-Pyrrolo[2,1,5-De]Quinolizine-4,6-Diol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets exacting research-grade specifications. A detailed Certificate of Analysis (COA) providing batch-specific data is supplied with every order to guarantee traceability and consistency for your critical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.