Description

2-Aza-Bicyclo[2.1.1]Hexane is a highly functionalized, strained bicyclic amine building block of significant interest in modern synthetic chemistry. Its unique bridged structure and nitrogen heteroatom make it a valuable precursor for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is primarily sought after by medicinal chemists and process R&D teams for applications in drug discovery, agrochemical synthesis, and advanced material science.

Application

• Pharmaceutical Intermediates: A key scaffold for synthesizing novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral drug candidates.
• Ligand Synthesis: Used in the preparation of sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology Probes: Employed in the synthesis of molecular probes to study enzyme function and biological pathways.
• Polymer Modification: Acts as a monomer or cross-linking agent for creating specialty polymers with tailored properties.
• Academic & Industrial R&D: A versatile reagent for methodological development and exploring new chemical space in synthetic organic chemistry.

Basic Information

Product Name	2-Aza-Bicyclo[2.1.1]Hexane
CAS No.	34392-24-0
Molecular Formula	C5H9N
Molecular Weight	83.13 g/mol
Synonyms	2-Azabicyclo[2.1.1]hexane; 1-Aza-4-bicyclo[2.1.1]hexane; Bicyclo[2.1.1]hexan-2-amine; 2-Azabicyclo[2.1.1]hexane; 2-Azabicyclo[2.1.1]hexane, 9CI; 2-Aza-bicyclo[2.1.1]hexane; 2-Azabicyclo[2.1.1]hexane (strain ring); 2-Azabicyclo[2.1.1]hexane hydrochloride (salts may have separate CAS numbers)
EINECS	Contact for details

Quality Control

Our 2-Aza-Bicyclo[2.1.1]Hexane is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support custom synthesis and can tailor specifications to meet specific project requirements, including compliance with ICH guidelines for impurity identification.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.