Description

2-Deoxy-D-Ribonic-1,4-Lactone is a specialized chiral lactone derivative of deoxyribose, serving as a high-value synthetic intermediate. This compound matters for its role in the precise construction of nucleoside analogs and other bioactive molecules, where its defined stereochemistry is critical. It is primarily needed by research institutions and pharmaceutical companies engaged in antiviral drug development, oligonucleotide synthesis, and advanced carbohydrate chemistry.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of nucleoside analogs for antiviral and anticancer therapeutics.
• Oligonucleotide Synthesis: Used in the research and development of modified DNA/RNA strands and antisense oligonucleotides.
• Carbohydrate Chemistry Research: A valuable precursor for synthesizing complex sugars and glycomimetics in academic and industrial R&D.
• Bioconjugation: Employed in the development of labeled probes and targeted drug delivery systems.
• Chemical Biology Tool: Serves as a substrate or inhibitor in enzymatic studies related to carbohydrate metabolism.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	2-Deoxy-D-Ribonic-1,4-Lactone
CAS No.	34371-14-7
Molecular Formula	C5H8O5
Molecular Weight	148.11 g/mol
Synonyms	2-Deoxy-D-ribono-1,4-lactone; 2-Deoxy-D-ribonic acid γ-lactone; D-2-Deoxyribono-1,4-lactone; 2-Deoxyribonolactone; (3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one; 2-Deoxy-D-erythro-pentono-1,4-lactone
EINECS	Contact for details

Quality Control

Our 2-Deoxy-D-Ribonic-1,4-Lactone is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and synthesis. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC/GC and chiral purity data. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.