Description

Spiro[Cyclopropane-1,9'-[9H]Fluorene]-2α,3α-Dicarboxylic Acid Dimethyl Ester is a high-purity, synthetically valuable spirocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique fused-ring structure provides a rigid, three-dimensional framework essential for developing novel materials and active pharmaceutical ingredients (APIs). This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in developing new generations of herbicides and pesticides with enhanced specificity and lower environmental impact.
• Ligand & Catalyst Development: Serves as a precursor for creating sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: A building block for organic light-emitting diodes (OLEDs) and other advanced electronic materials due to its fluorene-based, rigid structure.
• Academic & Industrial R&D: Employed in methodological studies and exploration of new spiroannulation and cyclopropanation reactions.
• Fine Chemical Synthesis: Utilized in the multi-step synthesis of complex natural product analogs and other high-value specialty chemicals.

Basic Information

Product Name	Spiro[Cyclopropane-1,9'-[9H]Fluorene]-2α,3α-Dicarboxylic Acid Dimethyl Ester
CAS No.	34296-55-4
Molecular Formula	C20H16O4
Molecular Weight	320.34 g/mol
Synonyms	Dimethyl Spiro[cyclopropane-1,9'-fluorene]-2α,3α-dicarboxylate; 2α,3α-Dicarbomethoxy-1,1a,1b,1c,2,3,4,5,10,10a-decahydrodicyclopropa[a,j]anthracene-7,12-dione (related); Fluorene-9-spiro-2'-cyclopropane-α,α'-dicarboxylic acid dimethyl ester; Spiro(cyclopropane-1,9'-fluorene)-2α,3α-dicarboxylic acid dimethyl ester; SCDFE-DM Ester; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Spiro[Cyclopropane-1,9'-[9H]Fluorene]-2α,3α-Dicarboxylic Acid Dimethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, NMR, and MS for structural confirmation, to ensure compliance with exacting R&D and process chemistry standards. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong alkalis and incompatible organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.