Description

[R,(-)]-2,3-Dihydro-3-Hydroxy-6-(2-Hydroxyethyl)-2,2,5,7-Tetramethyl-1H-Indene-1-One is a high-purity, chiral indanone derivative of significant interest in advanced organic synthesis. This compound serves as a critical building block and chiral intermediate for the development of complex molecules with specific stereochemistry. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in producing active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel drug candidates, particularly in therapeutic areas requiring specific enantiomeric purity.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where stereochemistry impacts biological activity.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development of new catalytic systems for stereoselective reactions.
• Fine Chemical Production: A valuable intermediate for manufacturing complex fragrance compounds, flavors, and other high-value specialty chemicals.
• Material Science Research: Potential building block for chiral polymers or advanced organic materials with specific optical properties.

Basic Information

Product Name	[R,(-)]-2,3-Dihydro-3-Hydroxy-6-(2-Hydroxyethyl)-2,2,5,7-Tetramethyl-1H-Indene-1-One
CAS No.	34169-70-5
Molecular Formula	C₁₅H₂₂O₃
Molecular Weight	250.33 g/mol
Synonyms	(-)-2,3-Dihydro-3-hydroxy-6-(2-hydroxyethyl)-2,2,5,7-tetramethyl-1H-inden-1-one; (R)-3-Hydroxy-6-(2-hydroxyethyl)-2,2,5,7-tetramethyl-2,3-dihydro-1H-inden-1-one; (R)-(-)-α-Tocopherol Metabolite Intermediate; Chiral Indanone Derivative; Levotofisopam Intermediate; (3R)-3-Hydroxy-2,2,5,7-tetramethyl-6-(2-hydroxyethyl)-2,3-dihydro-1H-inden-1-one
EINECS	Contact for details

Quality Control

Our production of [R,(-)]-2,3-Dihydro-3-Hydroxy-6-(2-Hydroxyethyl)-2,2,5,7-Tetramethyl-1H-Indene-1-One adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) determination by HPLC, to ensure it meets the exacting standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% e.e.
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.