Description

(Dichlorophosphinyl)Acetyl Chloride is a highly reactive organophosphorus compound that serves as a critical building block in advanced chemical synthesis. Its bifunctional nature, featuring both an acid chloride and a dichlorophosphinyl group, makes it an invaluable reagent for introducing phosphoryl and carbonyl functionalities in a single step. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly those with phosphorus-containing pharmacophores.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators requiring specific phosphoryl-acetyl motifs.
• Ligand and Catalyst Precursor: Serves as a starting material for the preparation of specialized phosphine-based ligands and organocatalysts.
• Polymer Chemistry: Employed in the synthesis of specialty polymers and flame retardants where phosphorus incorporation is desired.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D focused on organophosphorus chemistry and new synthetic methodologies.
• Peptide Modification: Potential use in the selective modification of peptides and proteins to introduce phosphoryl groups.

Basic Information

Product Name	(Dichlorophosphinyl)Acetyl Chloride
CAS No.	34164-06-2
Molecular Formula	C2H2Cl3O2P
Molecular Weight	195.37 g/mol
Synonyms	Acetylphosphonic Dichloride; (Acetylphosphinyl) Dichloride; Phosphonoacetyl Dichloride; Acetylphosphonoyl Dichloride; 2-Oxo-2-phosphonoacetyl Chloride; Dichloro(2-oxo-2-phosphonoacetyl); Acetylphosphonic acid dichloride; (Dichlorophosphinoyl)acetyl chloride
EINECS	Contact for details

Quality Control

Our (Dichlorophosphinyl)Acetyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong bases, oxidizers, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.