Description

(7R)-6,7,7Aβ,8-Tetrahydro-7-Methyl-5H-Benzo[G]-1,3-Benzodioxolo[6,5,4-De]Quinolin-12-Ol 7-Oxide is a complex, chiral isoquinoline alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound matters as a sophisticated chemical building block and a potential pharmacological intermediate for developing novel therapeutic agents. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on neurology, analgesia, and receptor-targeted drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel central nervous system (CNS) active compounds and potential analgesics.
• Biochemical Research: Used as a reference standard or ligand in studies targeting specific opioid or other G-protein coupled receptors (GPCRs) due to its structural complexity.
• Asymmetric Synthesis: Employed as a chiral scaffold or template in advanced catalytic and stoichiometric asymmetric transformations to construct complex molecular architectures.
• Medicinal Chemistry Exploration: Acts as a core structure for structure-activity relationship (SAR) studies aimed at optimizing potency, selectivity, and metabolic stability of new chemical entities.
• Process Chemistry Development: Used in scaling up and optimizing synthetic routes for related alkaloid-based active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for methodological development in heterocyclic and natural product synthesis.

Basic Information

Product Name	(7R)-6,7,7Aβ,8-Tetrahydro-7-Methyl-5H-Benzo[G]-1,3-Benzodioxolo[6,5,4-De]Quinolin-12-Ol 7-Oxide
CAS No.	34029-94-2
Molecular Formula	C19H17NO4
Molecular Weight	323.34 g/mol
Synonyms	7-Hydroxy-7-methyl-6,7,7aβ,8-tetrahydro-5H-[1,3]dioxolo[4',5':4,5]benzo[1,2-g]quinolin-12-ol 7-oxide; (7R)-7-Methyl-6,7,7aβ,8-tetrahydro-5H-[1,3]benzodioxolo[6,5,4-de]quinolin-12-ol 7-oxide; Salutaridine N-oxide (stereospecific); (7R)-Salutaridine N-Oxide; O6,O7-Dimethylthebaine N-oxide derivative; Isoquinoline alkaloid oxide; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (7R)-6,7,7Aβ,8-Tetrahydro-7-Methyl-5H-Benzo[G]-1,3-Benzodioxolo[6,5,4-De]Quinolin-12-Ol 7-Oxide is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification (NMR, MS, IR). Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent potential degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.