Description

3-Methoxy-L-Phenylalanine is a non-natural, chiral amino acid derivative featuring a methoxy substituent on the phenyl ring. This structural modification makes it a valuable synthetic intermediate and building block for advanced pharmaceutical research and fine chemical synthesis. It is primarily utilized in the development of peptide-based therapeutics, enzyme inhibitors, and as a precursor for novel active pharmaceutical ingredients (APIs). Industries requiring high-purity chiral compounds, such as pharmaceutical R&D, biotechnology, and specialty chemical manufacturing, are the key consumers of this material.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of peptide drugs and enzyme inhibitors targeting various therapeutic areas.
• Chiral Auxiliary/Synthon: Used in asymmetric synthesis to introduce chirality and the methoxyphenyl moiety into complex organic molecules.
• Biochemical Research: Employed in proteomics and metabolic pathway studies as a modified amino acid to probe enzyme specificity and function.
• API Development: Serves as a precursor in the research and process development of new Active Pharmaceutical Ingredients (APIs).
• Fine Chemical Synthesis: Utilized in custom synthesis and manufacturing of specialty chemicals, agrochemicals, and advanced materials.
• Standards & Reference Materials: Supplied as a high-purity standard for analytical method development and quality control in regulatory environments.

Basic Information

Product Name	3-Methoxy-L-Phenylalanine
CAS No.	33879-32-2
Molecular Formula	C₁₀H₁₃NO₃
Molecular Weight	195.22 g/mol
Synonyms	L-3-Methoxyphenylalanine; (S)-2-Amino-3-(3-methoxyphenyl)propanoic acid; 3-Methoxy-L-phenylalanine; (S)-3-Methoxyphenylalanine; 3-O-Methyl-L-phenylalanine; L-3-Methoxy-phenylalanine; H-3-OMe-Phe-OH; 3-Methoxy-DL-phenylalanine (related racemic mixture)
EINECS	Contact for details

Quality Control

Our 3-Methoxy-L-Phenylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets stringent specifications for pharmaceutical and research applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% (L-Isomer)
Loss on Drying	≤0.5%
Residue on Ignition (Sulfated Ash)	≤0.1%
Heavy Metals (as Pb)	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.