Description

(Dichloromethylene)Dimethylammonium Chloride is a versatile and highly reactive organic salt, primarily valued as a key reagent for the synthesis of complex molecules. Its core value proposition lies in its ability to act as a powerful chloromethylating or formylating agent, facilitating critical carbon-carbon and carbon-heteroatom bond-forming reactions. This makes it an essential building block for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for process development and scale-up.

Application

• Pharmaceutical Intermediate: A critical reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing chloromethyl or formyl groups into complex heterocycles and drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, where it serves as a key chloromethylation agent for constructing active molecular frameworks.
• Organic Synthesis Reagent: Employed in research laboratories and fine chemical production for Vilsmeier-Haack reactions, enabling the formylation of aromatic compounds and the synthesis of aldehydes.
• Dye & Pigment Manufacturing: Facilitates the chloromethylation of aromatic intermediates used in the production of specialized dyes and organic pigments.
• Polymer & Resin Modification: Acts as a functionalizing agent to introduce reactive chloromethyl groups onto polymer chains, modifying properties for specific industrial applications.
• Chemical Research & Development: A valuable tool for medicinal chemists and process chemists exploring new synthetic pathways and developing novel chemical entities.

Basic Information

Product Name	(Dichloromethylene)Dimethylammonium Chloride
CAS No.	33842-02-3
Molecular Formula	C3H6Cl3N
Molecular Weight	162.44 g/mol
Synonyms	Vilsmeier Reagent; N,N-Dimethylchloromethyleneiminium Chloride; Chloromethylene dimethylammonium chloride; (Chloromethylene)dimethylammonium chloride; 1-Chloro-N,N-dimethylmethaniminium chloride; DMF-Cl2 Complex; Vilsmeier-Haack Reagent; Vilsmeier Complex
EINECS	251-686-1

Quality Control

Our (Dichloromethylene)Dimethylammonium Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or lumps
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in polar organic solvents (e.g., DMF, DCM)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.