Description

[7S,(+)]-1,2,3,8,9,9Aα-Hexahydro-6-Hydroxy-5-Methoxy-1-Methylspiro[7H-Benzo[De]Quinoline-7,1'-Cyclohexane]-2'-Ene-4'-One is a high-purity, complex spirocyclic alkaloid derivative with a defined stereochemistry. This compound is valued as a critical advanced pharmaceutical intermediate and a versatile scaffold in organic synthesis for developing novel bioactive molecules. It is primarily required by pharmaceutical R&D and fine chemical synthesis laboratories engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of potential drug candidates targeting neurological and other disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Organic Synthesis: Acts as a sophisticated starting material for the synthesis of complex natural product analogs and novel heterocyclic compounds.
• Biochemical Research: Utilized in studies investigating enzyme inhibition or receptor binding due to its specific structural features.

Basic Information

Product Name	[7S,(+)]-1,2,3,8,9,9Aα-Hexahydro-6-Hydroxy-5-Methoxy-1-Methylspiro[7H-Benzo[De]Quinoline-7,1'-Cyclohexane]-2'-Ene-4'-One
CAS No.	33792-78-8
Molecular Formula	C22H27NO3
Molecular Weight	353.46 g/mol
Synonyms	(+)-7S-Hexahydrospiro[benzo[de]quinoline-7,1'-cyclohex-2'-en]-4'-one, 1,2,3,8,9,9aα-Hexahydro-6-hydroxy-5-methoxy-1-methyl-; Spiro[7H-benzo[de]quinoline-7,1'-cyclohexane]-2'-ene-4'-one derivative; 7S-HHSC; (7S)-1,2,3,8,9,9a-Hexahydro-6-hydroxy-5-methoxy-1-methylspiro[7H-benzo[de]quinoline-7,1'-cyclohex-2'-ene]-4'-one; Alkaloid Derivative 33792-78-8
EINECS	Contact for details

Quality Control

Our [7S,(+)]-1,2,3,8,9,9Aα-Hexahydro-6-Hydroxy-5-Methoxy-1-Methylspiro[7H-Benzo[De]Quinoline-7,1'-Cyclohexane]-2'-Ene-4'-One is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.