Description

(1R,5β)-4α-Methyl-1β-Isopropylbicyclo[3.1.0]Hexan-3α-Ol is a high-purity, stereochemically defined bicyclic terpene alcohol. This compound serves as a valuable chiral building block and intermediate in advanced organic synthesis, prized for its rigid molecular framework. It is essential for research and development chemists in the pharmaceutical and fine chemical industries seeking to create complex, optically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex stereochemistry.
• Fragrance & Flavor Chemistry: Used as a precursor for synthesizing unique, high-value aroma chemicals and flavor compounds with specific olfactory profiles.
• Agrochemical Research: Serves as a building block in the development of new, stereoselective pesticides and herbicides.
• Material Science: Investigated as a monomer or cross-linking agent for creating polymers with specialized thermal or mechanical properties.
• Catalyst & Ligand Development: The structure can be functionalized to create novel chiral ligands for asymmetric catalysis.
• Academic & Industrial R&D: A critical tool for methodological studies in organic synthesis, including cycloaddition and rearrangement reactions.

Basic Information

Product Name	(1R,5β)-4α-Methyl-1β-Isopropylbicyclo[3.1.0]Hexan-3α-Ol
CAS No.	33766-34-6
Molecular Formula	C10H18O
Molecular Weight	154.25 g/mol
Synonyms	4α-Methyl-1β-isopropylbicyclo[3.1.0]hexan-3α-ol; (1R,5S)-4-Methyl-1-(1-methylethyl)bicyclo[3.1.0]hexan-3-ol; 3-Thujanol; Sabinene hydrate (isomer); Bicyclo[3.1.0]hexan-3-ol, 4-methyl-1-(1-methylethyl)-, (1R,5S)-rel-; Terpene alcohol intermediate
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for this chiral intermediate. Production follows current Good Manufacturing Practice (cGMP) principles where applicable, and every batch is analyzed to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing assay, enantiomeric excess, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to prevent potential oxidation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.