Description

1,2-o-Isopropylidene-6-o-Trityl-α-D-Glucofuranose is a key protected carbohydrate intermediate, essential for the controlled synthesis of complex sugar derivatives. This compound matters because it provides a versatile scaffold for introducing specific functional groups at defined positions, enabling the production of high-value nucleosides, glycosides, and other bioactive molecules. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in carbohydrate chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of antiviral and anticancer nucleoside analogs.
• Glycosylation Reactions: Serves as a glycosyl donor or acceptor in the stereoselective synthesis of oligosaccharides and glycoconjugates.
• Carbohydrate Chemistry Research: Used in academic and industrial labs to study glycosidic bond formation and develop new synthetic methodologies.
• Fine Chemical Synthesis: Employed in the production of specialty chemicals, chiral ligands, and complex natural product derivatives.
• Protecting Group Strategy: The isopropylidene and trityl groups allow for selective deprotection, enabling multi-step synthetic sequences.

Basic Information

Product Name	1,2-o-Isopropylidene-6-o-Trityl-α-D-Glucofuranose
CAS No.	33737-08-5
Molecular Formula	C28H30O6
Molecular Weight	462.53 g/mol
Synonyms	1,2-O-Isopropylidene-6-O-trityl-α-D-glucofuranose; 6-O-Trityl-1,2-O-isopropylidene-α-D-glucofuranose; 1,2:5,6-Di-O-isopropylidene-α-D-glucofuranose 6-trityl ether; α-D-Glucofuranose, 1,2-O-(1-methylethylidene)-6-O-triphenylmethyl-; 6-O-Triphenylmethyl-1,2-O-isopropylidene-α-D-glucofuranose; 1,2-O-(1-Methylethylidene)-6-O-triphenylmethyl-α-D-glucofuranose; Tritylated isopropylidene glucose
EINECS	Contact for details

Quality Control

Our 1,2-o-Isopropylidene-6-o-Trityl-α-D-Glucofuranose is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, NMR, and optical rotation measurement, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]20/D	-15° to -20° (c=1 in CHCl3)
Melting Point	158°C - 162°C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.