Description

3-Chloro-4-Hydroxyphenylacetic Acid is a versatile chlorinated phenolic acid derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a phenolic hydroxyl and a carboxylic acid group, makes it a valuable building block for creating complex molecules with specific biological or material properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the production of herbicides and plant growth regulators, leveraging its phenolic structure for biological activity.
• Fine Chemical Building Block: Employed in organic synthesis for creating complex molecules, dyes, and liquid crystal materials.
• Biochemical Research: Serves as a standard or reagent in enzymatic studies and metabolic pathway analysis due to its structural similarity to natural phenolic acids.
• Polymer Modification: Acts as a functional monomer or additive to introduce chlorine and phenolic groups into polymer chains, altering material properties.

Basic Information

Product Name	3-Chloro-4-Hydroxyphenylacetic Acid
CAS No.	33697-81-3
Molecular Formula	C8H7ClO3
Molecular Weight	186.59 g/mol
Synonyms	(3-Chloro-4-hydroxyphenyl)acetic Acid; 2-(3-Chloro-4-hydroxyphenyl)acetic Acid; 4-Hydroxy-3-chlorophenylacetic Acid; 3-Chloro-4-hydroxybenzeneacetic Acid; CLPHPA; 33697-81-3; 3-Chloro-4-hydroxy-α-toluic Acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Hydroxyphenylacetic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting specifications for use in sensitive applications like pharmaceutical synthesis. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent absorption of atmospheric moisture, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158°C - 162°C
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.