Description

1-Chloro-4-(Ethoxymethyl)Benzene is a versatile aromatic ether derivative characterized by its chloromethyl and ethoxymethyl substituents. This compound is valued as a key chemical intermediate and building block in advanced organic synthesis, offering reactivity for further functionalization. It is primarily utilized by R&D laboratories and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a substituted benzyl ether moiety.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and insecticides, where its aromatic structure provides a stable core for bioactive molecules.
• Organic Synthesis Building Block: Functions as a versatile reagent for introducing the 4-(ethoxymethyl)phenyl group into more complex molecular architectures in fine chemical production.
• Liquid Crystal & Electronic Materials: Investigated as a potential intermediate in the synthesis of specialty monomers and compounds for advanced material science applications.
• Dye & Pigment Manufacturing: Acts as a starting material or intermediate in the production of specialized dyes and organic pigments.
• Cross-Coupling Reactions: Suitable for use in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) due to the presence of the chloro substituent.

Basic Information

Product Name	1-Chloro-4-(Ethoxymethyl)Benzene
CAS No.	33598-76-4
Molecular Formula	C9H11ClO
Molecular Weight	170.64 g/mol
Synonyms	4-Chlorobenzyl Ethyl Ether; p-Chlorobenzyl Ethyl Ether; 1-Chloro-4-(ethoxymethyl)benzene; (4-Chlorophenyl)methanol, ethyl ether; Ethyl 4-Chlorobenzyl Ether; Benzene, 1-chloro-4-(ethoxymethyl)-; α-Ethoxy-4-chlorotoluene
EINECS	Contact for details

Quality Control

Our 1-Chloro-4-(Ethoxymethyl)Benzene is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC and GC analysis, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.