Description

1-Methanesulfonyl-4-Phenylethynyl-Benzene is a specialized organic building block featuring a phenylethynyl group linked to a benzenesulfonyl moiety. This compound matters as a high-value intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs), where its unique structure enables precise molecular design. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced electronics industries for creating novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: Key synthon in the research and development of new drug candidates, particularly in kinase inhibitor and anti-cancer agent synthesis.
• Agrochemical Research: Used as a building block for developing novel pesticides and herbicides with specific activity profiles.
• Material Science: Serves as a precursor for organic semiconductors, liquid crystals, and other functional organic materials.
• Cross-Coupling Reactions: Utilized in Sonogashira, Suzuki, and other palladium-catalyzed cross-coupling reactions to construct complex molecular architectures.
• Chemical Biology: Acts as a probe or linker in bioconjugation and proteomics research due to its reactive alkyne group.
• Academic & Industrial R&D: Fundamental research chemical for exploring new organic reactions and synthetic methodologies.

Basic Information

Product Name	1-Methanesulfonyl-4-Phenylethynyl-Benzene
CAS No.	33592-56-2
Molecular Formula	C15H12O2S
Molecular Weight	256.32 g/mol
Synonyms	4-(Phenylethynyl)benzenesulfonylmethane; 1-(Methylsulfonyl)-4-(phenylethynyl)benzene; 4-Phenylethynylphenyl methyl sulfone; p-(Phenylethynyl)phenyl methyl sulfone; Methyl 4-(phenylethynyl)phenyl sulfone; [1,1'-Biphenyl]-4-yl methyl sulfone derivative; (4-Phenylethynylphenyl)(methyl)sulfone
EINECS	Contact for details

Quality Control

Our 1-Methanesulfonyl-4-Phenylethynyl-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.