Description

2-Ethynyl-Benzoic Acid is a specialized aromatic carboxylic acid derivative featuring a reactive ethynyl (acetylene) group. This unique bifunctional structure makes it a valuable high-purity building block for synthesizing complex organic molecules and advanced materials. It is primarily utilized by pharmaceutical research and fine chemical synthesis sectors for developing novel active compounds and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in oncology and neurology research.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and plant growth regulators with enhanced activity.
• Material Science: Monomer for the production of specialty polymers, resins, and advanced organic electronic materials.
• Ligand & Catalyst Development: Used to create complex chelating ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Research: Versatile reagent in academic and industrial R&D for exploring new organic reactions and molecular architectures.
• Fluorescent Probe Synthesis: Intermediate in the manufacture of dyes and molecular probes for bio-imaging and diagnostics.

Basic Information

Product Name	2-Ethynyl-Benzoic Acid
CAS No.	33578-00-6
Molecular Formula	C9H6O2
Molecular Weight	146.14 g/mol
Synonyms	2-Ethynylbenzoic Acid; Benzoic acid, 2-ethynyl-; o-Ethynylbenzoic Acid; 2-Carboxyphenylacetylene; (2-Carboxyphenyl)acetylene; 2-Ethynylbenzenecarboxylic acid; 2-Acetylene-benzoic acid; 2-(Ethynyl)benzoic acid
EINECS	Contact for details

Quality Control

Our 2-Ethynyl-Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, containers should be amber glass or opaque to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.