Description

Boc-1,4-Diaminobutane Hydrochloride is a protected diamine derivative, widely utilized as a crucial building block in organic synthesis and peptide chemistry. This compound is essential for introducing the 1,4-diaminobutane (putrescine) moiety into target molecules while providing orthogonal protection for the amine functionalities. It is primarily sought after by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for the development of active pharmaceutical ingredients (APIs), peptide-based therapeutics, and specialized chemical probes.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of polyamine analogs, enzyme inhibitors, and novel drug candidates targeting various diseases.
• Peptide Synthesis: Used to incorporate the putrescine unit into peptide chains, facilitating the creation of modified peptides with enhanced biological activity or stability.
• Cross-linking Agent: Serves as a precursor for the preparation of cross-linkers used in bioconjugation, material science, and polymer chemistry.
• Biochemical Research: Employed as a standard or reagent in studies related to polyamine metabolism, cell signaling, and molecular biology.
• Protecting Group Chemistry: The tert-butoxycarbonyl (Boc) group allows for selective deprotection under mild acidic conditions, enabling complex multi-step synthetic strategies.

Basic Information

Product Name	Boc-1,4-Diaminobutane Hydrochloride
CAS No.	33545-98-1
Molecular Formula	C9H21ClN2O2
Molecular Weight	224.73 g/mol
Synonyms	N1,N4-Bis(tert-butoxycarbonyl)-1,4-diaminobutane Hydrochloride; 1,4-Bis-Boc-putrescine Hydrochloride; N,N'-Di-Boc-1,4-diaminobutane HCl; Boc-Putrescine Hydrochloride; (4-((tert-Butoxycarbonyl)amino)butyl)carbamic acid tert-butyl ester hydrochloride; Di-Boc-putrescine HCl; N1,N4-Di-Boc-1,4-butanediamine Hydrochloride
EINECS	Contact for details

Quality Control

Our Boc-1,4-Diaminobutane Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material is suitable for demanding applications in research and cGMP-compliant synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.