Description

4-(1H-Imidazol-2-Yl)Butan-1-Amine Dihydrochloride is a high-purity, crystalline organic salt of significant interest in advanced chemical synthesis. This compound serves as a versatile and critical building block for the development of novel pharmaceutical intermediates and bioactive molecules. It is primarily required by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and life science sectors for applications in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of histamine H3 receptor antagonists and other biologically active compounds.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Development: Employed in the research and synthesis of novel crop protection agents and pesticides.
• Bioconjugation & Probe Synthesis: Utilized for modifying biomolecules or creating fluorescent probes for biochemical assays.
• Chemical Biology: Serves as a tool compound for studying enzyme inhibition and cellular signaling pathways.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing specialized fine chemicals.

Basic Information

Product Name	4-(1H-Imidazol-2-Yl)Butan-1-Amine Dihydrochloride
CAS No.	33544-92-2
Molecular Formula	C7H15Cl2N3
Molecular Weight	212.12 g/mol
Synonyms	2-(4-Aminobutyl)imidazole Dihydrochloride; 4-(2-Imidazolyl)butylamine Dihydrochloride; 1H-Imidazole-2-butaneamine Dihydrochloride; 4-(1H-Imidazol-2-yl)butan-1-amine Hydrochloride (1:2); 2-(4-Aminobutyl)-1H-imidazole Dihydrochloride; SKF-91488 Dihydrochloride (research code); Histamine H3 Antagonist Intermediate
EINECS	Contact for details

Quality Control

Our 4-(1H-Imidazol-2-Yl)Butan-1-Amine Dihydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for research and development. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.