Description

2-(Trifluoromethyl)-8-Naphthol is a specialized fluorinated naphthol derivative, a key building block in advanced organic synthesis. Its value lies in the unique combination of the naphthalene backbone and the electron-withdrawing trifluoromethyl group, which imparts significant chemical stability and influences reactivity profiles. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a critical intermediate for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring fluorinated aromatic systems to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), contributing to improved performance and durability.
• Polymer & Resin Modifier: Incorporated into specialty polymers to introduce fluorine, thereby enhancing chemical resistance, thermal stability, and surface properties of the final material.
• Dye & Pigment Intermediate: Utilized in the production of high-performance, light-fast dyes and pigments for industrial applications.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new fluorination chemistry and creating novel chemical entities.

Basic Information

Product Name	2-(Trifluoromethyl)-8-Naphthol
CAS No.	33533-46-9
Molecular Formula	C11H7F3O
Molecular Weight	212.17 g/mol
Synonyms	8-Hydroxy-2-(trifluoromethyl)naphthalene; 2-(Trifluoromethyl)naphthalen-8-ol; 2-Trifluoromethyl-8-naphthol; 2-Trifluoromethyl-8-hydroxynaphthalene; 8-Naphthol, 2-(trifluoromethyl)-; 2-TFM-8-Naphthol; α,α,α-Trifluoro-8-hydroxy-2-naphthalenemethanol (tautomer); β,β,β-Trifluoro-8-hydroxy-2-naphthaleneethanol (tautomer)
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)-8-Naphthol is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.