Description

(3Ar)-3Aβ,4,5,5A,6,7,8,9Bα-Octahydro-4β-Hydroxy-5Aα,9-Dimethyl-3-Methylenenaphtho[1,2-B]Furan-2(3H)-One is a complex, high-purity sesquiterpene lactone derivative with a defined stereochemistry. This compound is valued for its role as a critical synthetic intermediate and reference standard in advanced organic synthesis and pharmaceutical research. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures and developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel therapeutic agents, particularly in oncology and anti-inflammatory drug discovery.
• Reference Standard: Used for analytical method development, validation, and quality control in laboratories requiring high-purity chemical standards.
• Organic Synthesis Research: Acts as a versatile precursor for exploring new synthetic methodologies and constructing complex natural product analogs.
• Agrochemical Development: Investigated as an intermediate for creating new crop protection agents with specific biological activity.
• Academic & Institutional Research: Employed in university and institutional labs for studying structure-activity relationships (SAR) and reaction mechanisms.

Basic Information

Product Name	(3Ar)-3Aβ,4,5,5A,6,7,8,9Bα-Octahydro-4β-Hydroxy-5Aα,9-Dimethyl-3-Methylenenaphtho[1,2-B]Furan-2(3H)-One
CAS No.	33530-72-2
Molecular Formula	C15H20O3
Molecular Weight	248.32 g/mol
Synonyms	4β-Hydroxy-5α,9-dimethyldecahydro-3-methylenenaphtho[1,2-b]furan-2(3H)-one; 4β-Hydroxy-5α,9-dimethyl-3-methylenedecahydronaphtho[1,2-b]furan-2(3H)-one; (3aR,4S,5aR,9bS)-4-Hydroxy-5a,9-dimethyldecahydro-3-methylenenaphtho[1,2-b]furan-2(3H)-one; 3aβ,4,5,5a,6,7,8,9bα-Octahydro-4β-hydroxy-5aα,9-dimethyl-3-methylenenaphtho[1,2-b]furan-2(3H)-one; Parthenolide analog; Sesquiterpene lactone derivative.
EINECS	Contact for details

Quality Control

Our (3Ar)-3Aβ,4,5,5A,6,7,8,9Bα-Octahydro-4β-Hydroxy-5Aα,9-Dimethyl-3-Methylenenaphtho[1,2-B]Furan-2(3H)-One is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept tightly sealed to protect the product from moisture and potential contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.