Description

(1R,6As)-3Aβ,4,5,6,7,8,9,9A-Octahydro-9Aβ-Methyl-1H-1,6A-Ethanopyrido[2,1,6-De]Quinolizine CAS NO 33529-61-2 is a complex, polycyclic alkaloid derivative with a unique bridged ring structure. This compound serves as a critical advanced intermediate in the synthesis of complex pharmaceuticals and fine chemicals, where its stereochemistry is essential for biological activity. It is primarily required by pharmaceutical R&D laboratories and contract manufacturing organizations (CMOs) focused on developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex drug candidates, particularly in central nervous system (CNS) and anti-infective research.
• Organic Synthesis Research: Used in academic and industrial laboratories to study novel synthetic methodologies for constructing complex nitrogen-containing heterocycles.
• Asymmetric Catalysis: Serves as a precursor or ligand in the development of chiral catalysts for enantioselective transformations.
• Medicinal Chemistry: Provides a core scaffold for structure-activity relationship (SAR) studies aimed at discovering new bioactive molecules.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(1R,6As)-3Aβ,4,5,6,7,8,9,9A-Octahydro-9Aβ-Methyl-1H-1,6A-Ethanopyrido[2,1,6-De]Quinolizine
CAS No.	33529-61-2
Molecular Formula	C16H25N
Molecular Weight	231.38 g/mol
Synonyms	9aβ-Methyl-1H-1,6a-ethanopyrido[2,1,6-de]quinolizine, octahydro-, (1R,6aS)-; (1R,6aS)-Octahydro-9aβ-methyl-1H-1,6a-ethanopyrido[2,1,6-de]quinolizine; 1H-1,6a-Ethanopyrido[2,1,6-de]quinolizine, octahydro-9aβ-methyl-, (1R,6aS)-; A complex tricyclic amine; Bridged quinolizidine derivative
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems to ensure batch-to-batch consistency and purity. All materials are characterized using advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.