Description

4-Oxo-2,2,6,6-Tetramethylpiperidine-1-15N-1-Oxyl is a stable nitroxide radical compound, isotopically labeled with nitrogen-15 at the N-oxide position. This labeling is critical for advanced research applications requiring high sensitivity and specificity in detection and analysis. It serves as an essential spin label and probe in electron paramagnetic resonance (EPR) spectroscopy and related biophysical studies. Key industries that rely on this specialized reagent include pharmaceutical research, materials science, and academic institutions conducting mechanistic studies.

Application

• Spin Labeling in EPR Spectroscopy: Used as a stable free radical probe to study molecular dynamics, protein structure, and membrane fluidity.
• Polymer Chemistry Research: Acts as a mediator in controlled radical polymerization processes and for studying polymer degradation mechanisms.
• Biophysical & Structural Biology: Employed to investigate protein-protein interactions, conformational changes, and site-directed spin labeling (SDSL) experiments.
• Antioxidant Activity Studies: Serves as a model compound for researching radical scavenging and oxidative stress in biological systems.
• Magnetic Resonance Imaging (MRI) Contrast Agent Development: Used in the research and development of novel contrast agents due to its paramagnetic properties.
• Organic Synthesis & Catalysis: Functions as a catalyst or catalyst component in selective oxidation reactions.
• Nitrogen-15 Tracer Studies: The 15N label enables precise tracking in metabolic and environmental fate studies using advanced spectroscopic techniques.

Basic Information

Product Name	4-Oxo-2,2,6,6-Tetramethylpiperidine-1-15N-1-Oxyl
CAS No.	33490-11-8
Molecular Formula	C9H1615NO2
Molecular Weight	173.23 g/mol (for 15N labeled)
Synonyms	4-Oxo-TEMPO-15N; 4-Oxo-2,2,6,6-tetramethylpiperidine-1-oxyl-15N; 4-Oxo-TEMPO-15N-oxyl; 4-Oxo-2,2,6,6-tetramethyl-1-piperidinyloxy-15N; 4-Oxo-TEMPO radical-15N; 1-Oxyl-2,2,6,6-tetramethyl-4-piperidone-15N; 4-Oxo-TEMPO-15N free radical; 4-Oxo-2,2,6,6-tetramethylpiperidin-1-oxyl-15N
EINECS	Contact for details

Quality Control

Our 4-Oxo-2,2,6,6-Tetramethylpiperidine-1-15N-1-Oxyl is manufactured under strict quality protocols to ensure high isotopic and chemical purity for research applications. Each batch is characterized using advanced analytical techniques including NMR, EPR, and HPLC to confirm identity, isotopic enrichment, and radical content. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and specific tests is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as argon or nitrogen to maintain stability and purity. Keep away from strong reducing agents.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Identification (EPR)	Positive for nitroxide radical
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (15N)	≥ 98 atom %
Assay (EPR)	≥ 97.0%
Melting Point	Contact for details
Solubility	Soluble in common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.