Description

6-Bromo-4-Phenylquinazolin-2(1H)-One is a high-value, functionalized quinazolinone derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role as a versatile building block, enabling the construction of complex molecular architectures through its reactive bromine and ketone functionalities. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and plant growth regulators by leveraging the quinazolinone scaffold.
• Material Science: Serves as a monomer or functional unit in the design of organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology: Employed as a molecular probe or a tag in bioconjugation chemistry and proteomics research.
• Academic & Contract Research: Utilized in universities and CROs for methodological studies in heterocyclic and cross-coupling chemistry.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, high-value fine chemicals for client-specific projects.

Basic Information

Product Name	6-Bromo-4-Phenylquinazolin-2(1H)-One
CAS No.	33443-53-7
Molecular Formula	C₁₄H₉BrN₂O
Molecular Weight	301.14 g/mol
Synonyms	6-Bromo-4-phenyl-1,2-dihydroquinazolin-2-one; 6-Bromo-4-phenylquinazolin-2(1H)-one; 2(1H)-Quinazolinone, 6-bromo-4-phenyl-; 4-Phenyl-6-bromo-2(1H)-quinazolinone; 6-Bromo-4-phenyl-2(1H)-quinazolinone; 6-Bromo-4-phenyl-1H-quinazolin-2-one; 33443-53-7
EINECS	Contact for details

Quality Control

Our 6-Bromo-4-Phenylquinazolin-2(1H)-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.