Description

4-Chloro-6,7,8-Trimethoxyquinazoline is a high-purity, multi-functional quinazoline derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its versatile reactivity, particularly as a key intermediate in the development of complex pharmaceutical molecules and specialty fine chemicals. It is essential for research and production in the pharmaceutical, agrochemical, and material science industries, where precise chemical architecture is required.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of tyrosine kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides with specific modes of action.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport materials and emissive layer components.
• Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	4-Chloro-6,7,8-Trimethoxyquinazoline
CAS No.	33371-00-5
Molecular Formula	C₁₁H₁₁ClN₂O₃
Molecular Weight	254.67 g/mol
Synonyms	4-Chloro-6,7,8-trimethoxyquinazoline; 6,7,8-Trimethoxy-4-chloroquinazoline; 4-Chloro-6,7,8-trimethoxy-quinazoline; Quinazoline, 4-chloro-6,7,8-trimethoxy-; 33371-00-5; 4-Chloro-6,7,8-trimethoxy-quinazoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-6,7,8-Trimethoxyquinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports applications requiring GMP-grade intermediates and high-purity research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to minimize exposure to atmospheric moisture and light to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Single Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.