Description

1-(Cyclopropylmethyl)Quinazolin-4(1H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the quinazolinone class of heterocyclic compounds. This specialized chemical is critical for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions for clinical trial material production.
• Biochemical Tool Compound: May be utilized in the development of assay probes and biochemical tools for target validation and screening.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value organic molecules for various research applications.

Basic Information

Product Name	1-(Cyclopropylmethyl)Quinazolin-4(1H)-One
CAS No.	33319-11-8
Molecular Formula	C₁₂H₁₂N₂O
Molecular Weight	200.24 g/mol
Synonyms	1-(Cyclopropylmethyl)-4(1H)-quinazolinone; 4(1H)-Quinazolinone, 1-(cyclopropylmethyl)-; Quinazolin-4(1H)-one, 1-(cyclopropylmethyl)-; 1-Cyclopropylmethyl-1H-quinazolin-4-one; 1-(Cyclopropylmethyl)-1,4-dihydroquinazolin-4-one; CPQO
EINECS	Contact for details

Quality Control

Our 1-(Cyclopropylmethyl)Quinazolin-4(1H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by advanced analytical techniques including HPLC, GC, and NMR. We adhere to relevant industry standards and can provide material tailored to specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.