Description

Bis(Tricyclohexylphosphine)Palladium(0) is a highly active and air-sensitive organometallic catalyst widely used in cross-coupling reactions. Its value lies in its exceptional stability and selectivity, which are critical for constructing complex organic molecules in high yield and purity. This catalyst is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials industries, where it facilitates key synthetic steps in the production of active ingredients and specialty chemicals.

Application

• Suzuki-Miyaura Cross-Coupling: A premier catalyst for the coupling of aryl/vinyl boronic acids with aryl/vinyl halides, crucial for creating biaryl structures in drug discovery.
• Buchwald-Hartwig Amination: Enables the efficient formation of C-N bonds for synthesizing aryl amines, a common motif in pharmaceuticals and functional materials.
• Heck Reaction (Mizoroki-Heck): Catalyzes the coupling of alkenes with aryl halides for the synthesis of substituted alkenes.
• Negishi Coupling: Used for the cross-coupling of organozinc reagents with organic halides.
• Fine Chemical & Pharmaceutical Intermediates: Key for the scalable synthesis of complex intermediates in GMP and non-GMP manufacturing.
• Polymer & Materials Science: Facilitates the synthesis of conjugated polymers and organic electronic materials via controlled cross-coupling.
• Academic & Industrial R&D: A staple reagent in method development and exploratory synthesis within research laboratories.

Basic Information

Product Name	Bis(Tricyclohexylphosphine)Palladium(0)
CAS No.	33309-88-5
Molecular Formula	C₃₆H₆₆P₂Pd
Molecular Weight	699.23 g/mol
Synonyms	Palladium(0) bis(tricyclohexylphosphine); Pd(PCy₃)₂; Pd(0)-Tricyclohexylphosphine complex; Bis(trichlorohexylphosphine)palladium; Tris(dibenzylideneacetone)dipalladium(0) substitute; Pd(PCy3)2; Palladium-tricyclohexylphosphine catalyst; Tetrakis(triphenylphosphine)palladium(0) alternative
EINECS	Contact for details

Quality Control

Our Bis(Tricyclohexylphosphine)Palladium(0) is manufactured under strict quality protocols to ensure batch-to-batch consistency and high catalytic activity. Each lot is tested to confirm identity, purity, and performance in standard coupling reactions. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and residual solvent levels is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C. This compound is strictly light-sensitive (protect from all light exposure) and easily oxidized (store under inert atmosphere). Keep away from strong acid/organic solvent and fluoride/strong alkali. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (Pd content)	≥ 14.5 %
Purity (HPLC)	≥ 98.0 %
Solubility	Soluble in toluene, THF, DCM; insoluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.